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Home > Analytes > Urea/ BUN > Urea / BUN
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Urea / BUN
Overview
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Urea is the most important breakdown product of protein metabolism and is produced in the liver. Adults accumulate approximately 16 g of urea daily. This amount is mainly eliminated via the kidneys through glomerular filtration. About 40 - 50 % of urea is partially reabsorbed in the tubules. The rest is excreted via the intestines and perspiration.
Elevated urea levels are a clearly indication of renal insufficiency, but creatinine and urea do not reflect renal insufficiency to the same degree. Therefore both parameters should be tested at the same time to determine the degree of renal insufficiency.
Urea can be determined within minutes in the physician's office directly from capillary or venous whole blood with the Reflotron® Plus or Reflotron® sprint instruments using Reflotron® Urea.
REFLOTRON is a trademark of a member of the Roche group.
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