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GPT (ALT) Overview

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Overview

Glutamic-pyruvic transaminase (GPT) - also known as alanine aminotransferase or ALT - is a cytoplasmic hepatocellular enzyme, whose increase in blood is highly indicative for liver damage, e.g. by hepatitis, cirrhosis or hepatic tumors.
Serum values more than 15-fold above the upper reference limit always indicate an acute hepatocellular damage of either viral, toxic or circulatory origin. In most types of liver disease GPT activity is higher than that of glutamic-oxaloacetic transaminase (GOT); an exception is in alcoholic hepatitis. The ratio of GPT and GOT may provide further information about the severity of the disease and may serve as a prognostic indicator.

GPT (ALT) can be determined within minutes in the physician's office with the Reflotron® Plus or Reflotron® sprint instrument using Reflotron® GPT.

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