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Home > Analytes > Liver parameters > GOT (AST)
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GOT (AST)
Overview
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Glutamic-oxaloacetic transaminase (GOT) - also known as aspartate aminotransferase or AST, is an enzyme found in the mitochondrion and cytoplasm of all cells. The evaluation of GOT (AST) activity is a basic procedure for the diagnosis and the monitoring of hepatocellular disorders or muscle damage. The increase in GOT (AST) correlates in general well with the extent and severity of cellular damage.
The differential diagnosis of liver disease requires the determination of glutamic-pyruvic transaminase (GPT), γ-glutamyltransferase (GGT), and alkaline phosphatase (AP), in addition to GOT. The ratios of creatine kinase/GOT and GOT/GPT may provide further information about the organ damaged (liver vs. muscle) and the
severity of the disease.
GOT can be determined within minutes in the physician's office with the Reflotron® Plus or Reflotron® sprint instrument using Reflotron® GOT.
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