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Home > Analytes > Liver parameters > GGT
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GGT
Overview
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γ-Glutamyltransferase (GGT) is a highly sensitive parameter for numerous disorders with involvement of the liver, but it can also be found in pancreatic, renal disorders, and myocardial infarction. Usually it is regarded as one of the enzymes that indicate cholestasis. As GGT values rise before liver damage becomes evident this enzyme is especially important for diagnosis of anicteric or symptomless forms of disease. If the values increase two-fold or more above the upper reference level, a parenchymal liver damage has to be considered.
However, unexplained mild elevations are common and may occur even after moderate alcohol intake. For differential diagnosis it is therefore reasonable to take into account other enzyme parameters like glutamic-pyruvic transaminase (GPT), glutamic-oxaloacetic transaminase (GOT), alkaline phosphatase (ALP) or bilirubin, in addition to GGT.
GGT can be determined within minutes in the physician's office directly from capillary blood with the Reflotron® Plus or Reflotron® sprint instruments using Reflotron® GGT.
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