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Home > Analytes > Heart Parameters > Creatine kinase / CK

Creatine kinase / CK
Overview

Overview
Medical Background
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Overview

Creatine kinase (CK) is an enzyme that mainly occurs in muscles, heart and brain. Determination of CK activity is used for the diagnosis and monitoring of myocardial infarction and the monitoring of muscle diseases such as Duchenne progressive muscular dystrophy. Coronary heart disease and similar diseases are among the most frequent causes of death or early invalidity. In myocardial damage, such as in acute myocardial infarction, CK is released from destroyed myocardial cells. An increase of CK activity in the blood can be detected as early as 4 hours after the infarction. CK activity reaches its peak after 12 - 24 hours and returns to the reference range after 4 - 5 days.

CK can be determined in the physician's office with the Reflotron® Plus or Reflotron® sprint systems using Reflotron® CK. Sample material can be capillary blood, whole blood collected in standard sample collection tubes (as well as serum prepared from this blood), heparinized blood or heparinized plasma.

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